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Crystal structure of 1-{3-acetyl-2-(4-chlorophenyl)-6-hydroxy-4-[(2-hydroxypropyl)amino]-6-methylcyclohex-3-en-1-yl}ethanone
In the title compound, C(20)H(26)ClNO(4), the central cyclohexene ring adopts an approximate envelope conformation with the C atom binding with the hydroxy group at the tip of the flap. There is an intramolecular N—H⋯O hydrogen bond generating an S(6) ring motif. In the crystal, classical O—H⋯O hy...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420087/ https://www.ncbi.nlm.nih.gov/pubmed/25995954 http://dx.doi.org/10.1107/S2056989015008191 |
Sumario: | In the title compound, C(20)H(26)ClNO(4), the central cyclohexene ring adopts an approximate envelope conformation with the C atom binding with the hydroxy group at the tip of the flap. There is an intramolecular N—H⋯O hydrogen bond generating an S(6) ring motif. In the crystal, classical O—H⋯O hydrogen bonds and weak C—H⋯O and C—H⋯Cl interactions link the molecules, forming a three-dimensional supramolecular architecture. The crystal structure was refined as a four-component twin. |
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