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Crystal structure of 1-{3-acetyl-2-(4-chloro­phen­yl)-6-hy­droxy-4-[(2-hy­droxy­prop­yl)amino]-6-methyl­cyclo­hex-3-en-1-yl}ethanone

In the title compound, C(20)H(26)ClNO(4), the central cyclo­hexene ring adopts an approximate envelope conformation with the C atom binding with the hy­droxy group at the tip of the flap. There is an intramolecular N—H⋯O hydrogen bond generating an S(6) ring motif. In the crystal, classical O—H⋯O hy...

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Detalles Bibliográficos
Autores principales: Mohamed, Shaaban K., Mague, Joel T., Akkurt, Mehmet, Abdelhamid, Antar A., Albayati, Mustafa R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420087/
https://www.ncbi.nlm.nih.gov/pubmed/25995954
http://dx.doi.org/10.1107/S2056989015008191
Descripción
Sumario:In the title compound, C(20)H(26)ClNO(4), the central cyclo­hexene ring adopts an approximate envelope conformation with the C atom binding with the hy­droxy group at the tip of the flap. There is an intramolecular N—H⋯O hydrogen bond generating an S(6) ring motif. In the crystal, classical O—H⋯O hydrogen bonds and weak C—H⋯O and C—H⋯Cl inter­actions link the mol­ecules, forming a three-dimensional supra­molecular architecture. The crystal structure was refined as a four-component twin.