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Crystal structure of 11-(2,3-dimethoxyphenyl)-14-methyl-12-oxa-8,14-diazatetracyclo[8.3.3.0(1,10).0(2,7)]hexadeca-2(7),3,5-triene-9,13-dione
The title compound, C(22)H(22)N(2)O(5), contains two conformationally similar molecules (A and B) in its the asymmetric unit (r.m.s. overlay fit for the 29 non-H atoms = 0.194 Å). In each molecule, the lactone ring has an envelope conformation with the spiro C atom as the flap. In the crystal, A+A...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420094/ https://www.ncbi.nlm.nih.gov/pubmed/25995911 http://dx.doi.org/10.1107/S2056989015006386 |
Sumario: | The title compound, C(22)H(22)N(2)O(5), contains two conformationally similar molecules (A and B) in its the asymmetric unit (r.m.s. overlay fit for the 29 non-H atoms = 0.194 Å). In each molecule, the lactone ring has an envelope conformation with the spiro C atom as the flap. In the crystal, A+A and B+B inversion dimers linked by pairs of N—H⋯O hydrgen bonds occur; in both cases, R (2) (2)(8) loops are generated. A weak C—H⋯O interaction is also observed, which links the dimers into [010] chains. |
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