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Codelivery of antigen and an immune cell adhesion inhibitor is necessary for efficacy of soluble antigen arrays in experimental autoimmune encephalomyelitis

Autoimmune diseases such as multiple sclerosis (MS) are typified by the misrecognition of self-antigen and the clonal expansion of autoreactive T cells. Antigen-specific immunotherapies (antigen-SITs) have long been explored as a means to desensitize patients to offending self-antigen(s) with the po...

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Detalles Bibliográficos
Autores principales:	Sestak, Joshua O, Sullivan, Bradley P, Thati, Sharadvi, Northrup, Laura, Hartwell, Brittany, Antunez, Lorena, Forrest, M Laird, Vines, Charlotte M, Siahaan, Teruna J, Berkland, Cory
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420258/ https://www.ncbi.nlm.nih.gov/pubmed/26015953 http://dx.doi.org/10.1038/mtm.2014.8

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