Cargando…

mTORC1 Regulates Flagellin-Induced Inflammatory Response in Macrophages

Bacterial flagellin triggers inflammatory responses. Phosphoinositide 3-kinase (PI3K) and mammalian target of rapamycin (mTOR) regulate the production of pro- and anti-inflammatory cytokines that are induced by extrinsic antigens, but the function of mTORC1 in flagellin-induced inflammatory response...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bao, Wenlei, Wang, Yanfeng, Fu, Yuting, Jia, Xiaoyang, Li, Jiaxin, Vangan, Nyamtsengel, Bao, Lili, Hao, Huifang, Wang, Zhigang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420466/ https://www.ncbi.nlm.nih.gov/pubmed/25942007 http://dx.doi.org/10.1371/journal.pone.0125910

Ejemplares similares

Current Models of Mammalian Target of Rapamycin Complex 1 (mTORC1) Activation by Growth Factors and Amino Acids
por: Zheng, Xu, et al.
Publicado: (2014)

Inhibition of Mammalian Target of Rapamycin Complex 1 (mTORC1) Downregulates ELOVL1 Gene Expression and Fatty Acid Synthesis in Goat Fetal Fibroblasts
por: Wang, Weipeng, et al.
Publicado: (2015)

Inhibition of the mTORC1/NF-κB Axis Alters Amino Acid Metabolism in Human Hepatocytes
por: Zhang, Meng, et al.
Publicado: (2021)

A quantitative transcriptomic analysis of the physiological significance of mTOR signaling in goat fetal fibroblasts
por: Fu, Yuting, et al.
Publicado: (2016)

Pathogenic effects of inhibition of mTORC1/STAT3 axis facilitates Staphylococcus aureus-induced pyroptosis in human macrophages
por: Yao, Ruiyuan, et al.
Publicado: (2020)

Pathogenic Role of mTORC1 and mTORC2 in Pulmonary Hypertension
por: Tang, Haiyang, et al.
Publicado: (2018)

mTORC1 and mTORC2 in cancer and the tumor microenvironment
por: Kim, Laura C., et al.
Publicado: (2016)

Regulation of mTORC2 Signaling
por: Fu, Wenxiang, et al.
Publicado: (2020)

Defects in mTORC1 Network and mTORC1-STAT3 Pathway Crosstalk Contributes to Non-inflammatory Hepatocellular Carcinoma
por: Li, Ting, et al.
Publicado: (2020)

Both mTORC1 and mTORC2 are involved in the regulation of cell adhesion
por: Chen, Long, et al.
Publicado: (2015)

The metabolic waste ammonium regulates mTORC2 and mTORC1 signaling
por: Merhi, Ahmad, et al.
Publicado: (2017)

Activation of mTORC1 by LSECtin in macrophages directs intestinal repair in inflammatory bowel disease
por: Li, Qian, et al.
Publicado: (2020)

LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control
por: Gan, Wenjian, et al.
Publicado: (2020)

Exosome Release Is Regulated by mTORC1
por: Zou, Wenchong, et al.
Publicado: (2018)

mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation
por: Ding, Xiaolei, et al.
Publicado: (2016)

LPS Induces mTORC1 and mTORC2 Activation During Monocyte Adhesion
por: Ribeiro, Marcelle C., et al.
Publicado: (2018)

mTORC1 and mTORC2 differentially promote natural killer cell development
por: Yang, Chao, et al.
Publicado: (2018)

mTORC1 and mTORC2 are differentially engaged in the development of laser-induced CNV
por: Yang, Jin Young, et al.
Publicado: (2019)

Dopamine neuron morphology and output are differentially controlled by mTORC1 and mTORC2
por: Kosillo, Polina, et al.
Publicado: (2022)

Rapamycin inhibits mSin1 phosphorylation independently of mTORC1 and mTORC2
por: Luo, Yan, et al.
Publicado: (2015)

mTORC2, but not mTORC1, is required for hippocampal mGluR-LTD and associated behaviors
por: Zhu, Ping Jun, et al.
Publicado: (2018)

MiR-155 enhances phagocytosis of alveolar macrophages through the mTORC2/RhoA pathway
por: Yang, Xinna, et al.
Publicado: (2023)

mTORC2 Regulates Lipogenic Gene Expression through PPARγ to Control Lipid Synthesis in Bovine Mammary Epithelial Cells
por: Guo, Zhixin, et al.
Publicado: (2019)

Glutaminolysis feeds mTORC1
por: Durán, Raúl V., et al.
Publicado: (2012)

Regulation of adiposity by mTORC1
por: Magdalon, Juliana, et al.
Publicado: (2017)

mTORC2 Steals the Spotlight
por: Jansen, Laura A.
Publicado: (2020)

Something to mTORC About in NASH
por: Finck, Brian N.
Publicado: (2022)

Active-Site Inhibitors of mTOR Target Rapamycin-Resistant Outputs of mTORC1 and mTORC2
por: Feldman, Morris E, et al.
Publicado: (2009)

Influenza virus differentially activates mTORC1 and mTORC2 signaling to maximize late stage replication
por: Kuss-Duerkop, Sharon K., et al.
Publicado: (2017)

Regulation of Autophagy through TORC1 and mTORC1
por: Noda, Takeshi
Publicado: (2017)

Computational research of mTORC1 inhibitor on cerebral ischemia-reperfusion injury
por: Li, Hui, et al.
Publicado: (2021)

Crosstalks between mTORC1 and mTORC2 variagate cytokine signaling to control NK maturation and effector function
por: Wang, Fangjie, et al.
Publicado: (2018)

Differential regulation of mTORC1 and mTORC2 is critical for 8-Br-cAMP-induced decidualization
por: Baek, Mi-Ock, et al.
Publicado: (2018)

Genetic inactivation of mTORC1 or mTORC2 in neurons reveals distinct functions in glutamatergic synaptic transmission
por: McCabe, Matthew P, et al.
Publicado: (2020)

Hyperactivity of mTORC1 or mTORC2-dependent signaling causes epilepsy downstream of somatic PTEN loss
por: Cullen, Erin R., et al.
Publicado: (2023)

Regulation of mTORC1 by lysosomal calcium and calmodulin
por: Li, Ruo-Jing, et al.
Publicado: (2016)

mTORC1 signaling in hepatic lipid metabolism
por: Han, Jinbo, et al.
Publicado: (2017)

Combination of mTOR and EGFR Kinase Inhibitors Blocks mTORC1 and mTORC2 Kinase Activity and Suppresses the Progression of Colorectal Carcinoma
por: Wang, Quan, et al.
Publicado: (2013)

Discovery of RMC-5552, a Selective Bi-Steric Inhibitor of mTORC1, for the Treatment of mTORC1-Activated Tumors
por: Burnett, G. Leslie, et al.
Publicado: (2022)

Differential controls of MAIT cell effector polarization by mTORC1/mTORC2 via integrating cytokine and costimulatory signals
por: Tao, Huishan, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_2hq93i5ot1snulkrv16atrpeva