Prediction of distal residue participation in enzyme catalysis

A scoring method for the prediction of catalytically important residues in enzyme structures is presented and used to examine the participation of distal residues in enzyme catalysis. Scores are based on the Partial Order Optimum Likelihood (POOL) machine learning method, using computed electrostati...

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Detalles Bibliográficos
Autores principales: Brodkin, Heather R, DeLateur, Nicholas A, Somarowthu, Srinivas, Mills, Caitlyn L, Novak, Walter R, Beuning, Penny J, Ringe, Dagmar, Ondrechen, Mary Jo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420525/
https://www.ncbi.nlm.nih.gov/pubmed/25627867
http://dx.doi.org/10.1002/pro.2648

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