Cargando…

Functional Human Liver Preservation and Recovery by Means of Subnormothermic Machine Perfusion

There is currently a severe shortage of liver grafts available for transplantation. Novel organ preservation techniques are needed to expand the pool of donor livers. Machine perfusion of donor liver grafts is an alternative to traditional cold storage of livers and holds much promise as a modality...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bruinsma, Bote G., Avruch, James H., Weeder, Pepijn D., Sridharan, Gautham V., Uygun, Basak E., Karimian, Negin G., Porte, Robert J., Markmann, James F., Yeh, Heidi, Uygun, Korkut
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MyJove Corporation 2015
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420550/ https://www.ncbi.nlm.nih.gov/pubmed/25938299 http://dx.doi.org/10.3791/52777

Ejemplares similares

Metabolic profiling during ex vivo machine perfusion of the human liver
por: Bruinsma, Bote G., et al.
Publicado: (2016)

Endothelial Dysfunction in Steatotic Human Donor Livers: A Pilot Study of the Underlying Mechanism During Subnormothermic Machine Perfusion
por: Beijert, Irene, et al.
Publicado: (2018)

Subnormothermic Machine Perfusion of Steatotic Livers Results in Increased Energy Charge at the Cost of Anti-Oxidant Capacity Compared to Normothermic Perfusion
por: Karimian, Negin, et al.
Publicado: (2019)

Abstract: Ex-vivo Subnormothermic Oxygenated Machine Perfusion of Swine Forelimbs Enables Prolonged Graft Preservation Prior to Transplantation
por: Lellouch, Alexandre G., et al.
Publicado: (2016)

A simplified subnormothermic machine perfusion system restores ischemically damaged liver grafts in a rat model of orthotopic liver transplantation
por: Berendsen, Tim A, et al.
Publicado: (2012)

Warm Ischemic Injury Is Reflected in the Release of Injury Markers during Cold Preservation of the Human Liver
por: Bruinsma, Bote G., et al.
Publicado: (2015)

Metabolomic Modularity Analysis (MMA) to Quantify Human Liver Perfusion Dynamics
por: Sridharan, Gautham Vivek, et al.
Publicado: (2017)

The efficacy of HBOC‐201 in ex situ gradual rewarming kidney perfusion in a rat model
por: Mahboub, Paria, et al.
Publicado: (2019)

Subnormothermic Ex Vivo Porcine Kidney Perfusion Improves Energy Metabolism: Analysis Using (31)P Magnetic Resonance Spectroscopic Imaging
por: Agius, Thomas, et al.
Publicado: (2022)

Tryptophan Metabolism via the Kynurenine Pathway: Implications for Graft Optimization during Machine Perfusion
por: Zhang, Anna, et al.
Publicado: (2020)

Split-Liver Ex Situ Machine Perfusion: A Novel Technique for Studying Organ Preservation and Therapeutic Interventions
por: Huang, Viola, et al.
Publicado: (2020)

Metabolic and lipidomic profiling of steatotic human livers during ex situ normothermic machine perfusion guides resuscitation strategies
por: Raigani, Siavash, et al.
Publicado: (2020)

A fitness index for transplantation of machine-perfused cadaveric rat livers
por: Perk, Sinem, et al.
Publicado: (2012)

Resuscitation of Ischemic Donor Livers with Normothermic Machine Perfusion: A Metabolic Flux Analysis of Treatment in Rats
por: Izamis, Maria-Louisa, et al.
Publicado: (2013)

The effect of blood cells retained in rat livers during static cold storage on viability outcomes during normothermic machine perfusion
por: Haque, Omar, et al.
Publicado: (2021)

Supercooling as a Viable Non-Freezing Cell Preservation Method of Rat Hepatocytes
por: Usta, O. Berk, et al.
Publicado: (2013)

Tissue heterogeneity in structure and conductivity contribute to cell survival during irreversible electroporation ablation by “electric field sinks”
por: Golberg, Alexander, et al.
Publicado: (2015)

A Metabolic Index of Ischemic Injury for Perfusion-Recovery of Cadaveric Rat Livers
por: Perk, Sinem, et al.
Publicado: (2011)

Thrombolytic Therapy During ex-vivo Normothermic Machine Perfusion of Human Livers Reduces Peribiliary Vascular Plexus Injury
por: Haque, Omar, et al.
Publicado: (2021)

Successful Supercooled Liver Storage for 4 Days
por: Berendsen, Tim A., et al.
Publicado: (2014)

A Comparative Study of Single and Dual Perfusion During End-ischemic Subnormothermic Liver Machine Preservation
por: Brüggenwirth, Isabel M.A., et al.
Publicado: (2018)

Subnormothermic Oxygenated Perfusion Optimally Preserves Donor Kidneys Ex Vivo
por: Bhattacharjee, Rabindra N., et al.
Publicado: (2019)

Rat liver regeneration following ablation with irreversible electroporation
por: Golberg, Alexander, et al.
Publicado: (2016)

121. Acellular Subnomothermic Machine Perfusion of Fasciocutaneous Flaps in Swine
por: Berkane, Yanis, et al.
Publicado: (2023)

Anti-apoptotic treatment of warm ischemic male rat livers in machine perfusion improves symptoms of ischemia-reperfusion injury
por: Mojoudi, Mohammadreza, et al.
Publicado: (2023)

Development of a rat forelimb vascularized composite allograft (VCA) perfusion protocol
por: Pendexter, Casie A., et al.
Publicado: (2023)

Layer-by-layer heparinization of decellularized liver matrices to reduce thrombogenicity of tissue engineered grafts
por: Bruinsma, Bote G, et al.
Publicado: (2015)

Subnormothermic Ex Vivo Lung Perfusion Temperature Improves Graft Preservation in Lung Transplantation
por: Arni, Stephan, et al.
Publicado: (2021)

Pan-caspase inhibition during normothermic machine perfusion of discarded livers mitigates ex situ innate immune responses
por: Raigani, Siavash, et al.
Publicado: (2022)

Development of Metabolic Indicators of Burn Injury: Very Low Density Lipoprotein (VLDL) and Acetoacetate Are Highly Correlated to Severity of Burn Injury in Rats
por: Izamis, Maria-Louisa, et al.
Publicado: (2012)

Criteria for Viability Assessment of Discarded Human Donor Livers during Ex Vivo Normothermic Machine Perfusion
por: Sutton, Michael E., et al.
Publicado: (2014)

Decreased apoptosis in fatty livers submitted to subnormothermic machine-perfusion respect to cold storage
por: Boncompagni, E., et al.
Publicado: (2011)

Subnormothermic Perfusion in the Isolated Rat Liver Preserves the Antioxidant Glutathione and Enhances the Function of the Ubiquitin Proteasome System
por: Carbonell, Teresa, et al.
Publicado: (2016)

Cell release during perfusion reflects cold ischemic injury in rat livers
por: de Vries, Reinier J., et al.
Publicado: (2020)

Sodium Hydrosulfide Treatment During Porcine Kidney Ex Vivo Perfusion and Transplantation
por: Agius, Thomas, et al.
Publicado: (2023)

4072 Optimizing ex-vivo perfusion in Vascularized Composite Allotransplantation using Hyperosmolar solution and Electric Stimulation: Preliminary Results – ERRATUM
por: Jonczyk, Michael, et al.
Publicado: (2023)

Liver Preservation With Machine Perfusion and a Newly Developed Cell‐Free Oxygen Carrier Solution Under Subnormothermic Conditions
por: Fontes, P., et al.
Publicado: (2015)

Improvement of steatotic rat liver function with a defatting cocktail during ex situ normothermic machine perfusion is not directly related to liver fat content
por: Raigani, Siavash, et al.
Publicado: (2020)

Technique of Subnormothermic Ex Vivo Liver Perfusion for the Storage, Assessment, and Repair of Marginal Liver Grafts
por: Knaak, Jan M., et al.
Publicado: (2014)

Evaluating the Effects of Subnormothermic Perfusion with AP39 in a Novel Blood-Free Model of Ex Vivo Kidney Preservation and Reperfusion
por: Juriasingani, Smriti, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_2fc8ct6t0s99tvnscrd5n5ule4