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The regulation of connective tissue growth factor expression influences the viability of human trabecular meshwork cells

Connective tissue growth factor (CTGF) induces extracellular matrix (ECM) synthesis and contractility in human trabecular meshwork (HTM) cells. Both processes are involved in the pathogenesis of primary open-angle glaucoma. To date, little is known about regulation and function of CTGF expression in...

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Detalles Bibliográficos
Autores principales: Kuespert, Sabrina, Junglas, Benjamin, Braunger, Barbara M, Tamm, Ernst R, Fuchshofer, Rudolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420603/
https://www.ncbi.nlm.nih.gov/pubmed/25704370
http://dx.doi.org/10.1111/jcmm.12492