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Oligomerized CARD16 promotes caspase-1 assembly and IL-1β processing
Increasing evidence indicates that caspase recruitment domain (CARD)-mediated caspase-1 (CASP1) assembly is an essential process for its activation and subsequent interleukin (IL)-1β release, leading to the initiation of inflammation. Both CARD16 and CARD17 were previously reported as inhibitory hom...
Autores principales: | Karasawa, Tadayoshi, Kawashima, Akira, Usui, Fumitake, Kimura, Hiroaki, Shirasuna, Koumei, Inoue, Yoshiyuki, Komada, Takanori, Kobayashi, Motoi, Mizushina, Yoshiko, Sagara, Junji, Takahashi, Masafumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420773/ https://www.ncbi.nlm.nih.gov/pubmed/25973362 http://dx.doi.org/10.1016/j.fob.2015.04.011 |
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