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TAK-242, an antagonist for Toll-like receptor 4, protects against acute cerebral ischemia/reperfusion injury in mice

Toll-like receptor 4 (TLR4) contributes to cerebral ischemia/reperfusion (I/R) injury and is a potential target for the treatment of ischemic stroke. This experiment is to evaluate the effect of an exogenous TLR4 antagonist, TAK-242, against acute cerebral I/R injury. A mouse model of cerebral I/R w...

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Detalles Bibliográficos
Autores principales:	Hua, Fang, Tang, Huiling, Wang, Jun, Prunty, Megan C, Hua, Xiaodong, Sayeed, Iqbal, Stein, Donald G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Rapid Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420883/ https://www.ncbi.nlm.nih.gov/pubmed/25586141 http://dx.doi.org/10.1038/jcbfm.2014.240

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