Rituximab in two cases of Goodpasture's syndrome

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We describe the effects of rituximab in two patients with refractory Goodpasture's syndrome. After one single 1000 mg dose administration, rituximab did not appear to improve renal function in either of our cases. Polyoma virus-negative leukoencephalopathy, a probable toxic side effect of ritux...

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Detalles Bibliográficos
Autores principales: Schless, Birgit, Yildirim, Suzan, Beha, Daniel, Keller, Frieder, Czock, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421183/
https://www.ncbi.nlm.nih.gov/pubmed/25983996
http://dx.doi.org/10.1093/ndtplus/sfp020
Descripción
Sumario:We describe the effects of rituximab in two patients with refractory Goodpasture's syndrome. After one single 1000 mg dose administration, rituximab did not appear to improve renal function in either of our cases. Polyoma virus-negative leukoencephalopathy, a probable toxic side effect of rituximab, was seen in our first patient.

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