Late recovery of renal failure after autologous haematopoietic stem cell transplantation for multiple myeloma: a report of two cases

Acute renal failure is a frequent feature in patients with multiple myeloma (MM). MM-related renal insufficiency may improve after autologous haematopoietic stem cell transplantation (autoHSCT) even in patients initially requiring dialysis. Herein, we report on two unusual cases of late improvement...

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Autores principales: Bigé, Naïke, Guéry, Bruno, Delarue, Richard, Noël, Laure-Hélène, Fakhouri, Fadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421199/
https://www.ncbi.nlm.nih.gov/pubmed/25984001
http://dx.doi.org/10.1093/ndtplus/sfp013
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author Bigé, Naïke
Guéry, Bruno
Delarue, Richard
Noël, Laure-Hélène
Fakhouri, Fadi
author_facet Bigé, Naïke
Guéry, Bruno
Delarue, Richard
Noël, Laure-Hélène
Fakhouri, Fadi
author_sort Bigé, Naïke
collection PubMed
description Acute renal failure is a frequent feature in patients with multiple myeloma (MM). MM-related renal insufficiency may improve after autologous haematopoietic stem cell transplantation (autoHSCT) even in patients initially requiring dialysis. Herein, we report on two unusual cases of late improvement in renal function occurring over more than 5 years after autoHSCT for MM. Clinicians must be aware that slow and progressive improvement in renal function may occur over years in patients with MM-associated renal failure. Our data underline the need for an aggressive treatment, including autoHSCT, in MM patients presenting with severe renal dysfunction.
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spelling pubmed-44211992015-05-15 Late recovery of renal failure after autologous haematopoietic stem cell transplantation for multiple myeloma: a report of two cases Bigé, Naïke Guéry, Bruno Delarue, Richard Noël, Laure-Hélène Fakhouri, Fadi NDT Plus Case Report Acute renal failure is a frequent feature in patients with multiple myeloma (MM). MM-related renal insufficiency may improve after autologous haematopoietic stem cell transplantation (autoHSCT) even in patients initially requiring dialysis. Herein, we report on two unusual cases of late improvement in renal function occurring over more than 5 years after autoHSCT for MM. Clinicians must be aware that slow and progressive improvement in renal function may occur over years in patients with MM-associated renal failure. Our data underline the need for an aggressive treatment, including autoHSCT, in MM patients presenting with severe renal dysfunction. Oxford University Press 2009-06 2009-02-09 /pmc/articles/PMC4421199/ /pubmed/25984001 http://dx.doi.org/10.1093/ndtplus/sfp013 Text en © The Author [2009]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Bigé, Naïke
Guéry, Bruno
Delarue, Richard
Noël, Laure-Hélène
Fakhouri, Fadi
Late recovery of renal failure after autologous haematopoietic stem cell transplantation for multiple myeloma: a report of two cases
title Late recovery of renal failure after autologous haematopoietic stem cell transplantation for multiple myeloma: a report of two cases
title_full Late recovery of renal failure after autologous haematopoietic stem cell transplantation for multiple myeloma: a report of two cases
title_fullStr Late recovery of renal failure after autologous haematopoietic stem cell transplantation for multiple myeloma: a report of two cases
title_full_unstemmed Late recovery of renal failure after autologous haematopoietic stem cell transplantation for multiple myeloma: a report of two cases
title_short Late recovery of renal failure after autologous haematopoietic stem cell transplantation for multiple myeloma: a report of two cases
title_sort late recovery of renal failure after autologous haematopoietic stem cell transplantation for multiple myeloma: a report of two cases
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421199/
https://www.ncbi.nlm.nih.gov/pubmed/25984001
http://dx.doi.org/10.1093/ndtplus/sfp013
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