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Clinical and histological features of lupus nephritis induced by anti-TNFα therapy
It is known that anti-TNFα therapy has opened a new era in treatment of rheumatoid arthritis, and it is emerging as a new successful treatment in the current rheumatologic practice. Besides, there is evidence that this therapy is an important cause of iatrogenic autoimmune disease. Several studies r...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421221/ https://www.ncbi.nlm.nih.gov/pubmed/25983886 http://dx.doi.org/10.1093/ndtplus/sfn060 |
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author | Piccolo, Tiziana Lisi, Piero Valicenti, Enza Pannarale, Giovanni Coratelli, Pasquale |
author_facet | Piccolo, Tiziana Lisi, Piero Valicenti, Enza Pannarale, Giovanni Coratelli, Pasquale |
author_sort | Piccolo, Tiziana |
collection | PubMed |
description | It is known that anti-TNFα therapy has opened a new era in treatment of rheumatoid arthritis, and it is emerging as a new successful treatment in the current rheumatologic practice. Besides, there is evidence that this therapy is an important cause of iatrogenic autoimmune disease. Several studies reported the possible onset of lupus syndrome that can be resolved with withdrawal of anti-TNFα drugs. Our report describes the first lupus nephritis case developing in a rapidly progressive renal failure that required haemodialysis treatment in a patient affected with rheumatoid arthritis, treated with anti-TNFα therapy. So, we confirm the importance of a careful clinic and immunologic evaluation before starting anti-TNFα therapy. |
format | Online Article Text |
id | pubmed-4421221 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-44212212015-05-15 Clinical and histological features of lupus nephritis induced by anti-TNFα therapy Piccolo, Tiziana Lisi, Piero Valicenti, Enza Pannarale, Giovanni Coratelli, Pasquale NDT Plus Case Report It is known that anti-TNFα therapy has opened a new era in treatment of rheumatoid arthritis, and it is emerging as a new successful treatment in the current rheumatologic practice. Besides, there is evidence that this therapy is an important cause of iatrogenic autoimmune disease. Several studies reported the possible onset of lupus syndrome that can be resolved with withdrawal of anti-TNFα drugs. Our report describes the first lupus nephritis case developing in a rapidly progressive renal failure that required haemodialysis treatment in a patient affected with rheumatoid arthritis, treated with anti-TNFα therapy. So, we confirm the importance of a careful clinic and immunologic evaluation before starting anti-TNFα therapy. Oxford University Press 2008-08 2008-06-17 /pmc/articles/PMC4421221/ /pubmed/25983886 http://dx.doi.org/10.1093/ndtplus/sfn060 Text en © The Author [2008]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Case Report Piccolo, Tiziana Lisi, Piero Valicenti, Enza Pannarale, Giovanni Coratelli, Pasquale Clinical and histological features of lupus nephritis induced by anti-TNFα therapy |
title | Clinical and histological features of lupus nephritis induced by anti-TNFα therapy |
title_full | Clinical and histological features of lupus nephritis induced by anti-TNFα therapy |
title_fullStr | Clinical and histological features of lupus nephritis induced by anti-TNFα therapy |
title_full_unstemmed | Clinical and histological features of lupus nephritis induced by anti-TNFα therapy |
title_short | Clinical and histological features of lupus nephritis induced by anti-TNFα therapy |
title_sort | clinical and histological features of lupus nephritis induced by anti-tnfα therapy |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421221/ https://www.ncbi.nlm.nih.gov/pubmed/25983886 http://dx.doi.org/10.1093/ndtplus/sfn060 |
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