A case of adult atypical haemolytic uraemic syndrome related to anti-factor H autoantibodies successfully treated by plasma exchange, corticosteroids and rituximab

Complement factor H auto-antibodies (CFH-ab) are a rare cause (6–10%) of atypical haemolytic uraemic syndrome (aHUS). All observations previously described were retrospective and occurred in children or teenagers. We report the first case of aHUS associated with anti-CFH antibodies in an adult patie...

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Autores principales: Lionet, Arnaud, Provôt, François, Glowacki, François, Frémeaux-Bacchi, Veronique, Hazzan, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421306/
https://www.ncbi.nlm.nih.gov/pubmed/25984036
http://dx.doi.org/10.1093/ndtplus/sfp109
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author Lionet, Arnaud
Provôt, François
Glowacki, François
Frémeaux-Bacchi, Veronique
Hazzan, Marc
author_facet Lionet, Arnaud
Provôt, François
Glowacki, François
Frémeaux-Bacchi, Veronique
Hazzan, Marc
author_sort Lionet, Arnaud
collection PubMed
description Complement factor H auto-antibodies (CFH-ab) are a rare cause (6–10%) of atypical haemolytic uraemic syndrome (aHUS). All observations previously described were retrospective and occurred in children or teenagers. We report the first case of aHUS associated with anti-CFH antibodies in an adult patient who was successfully treated by plasma exchange, corticosteroids and rituximab.
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spelling pubmed-44213062015-05-15 A case of adult atypical haemolytic uraemic syndrome related to anti-factor H autoantibodies successfully treated by plasma exchange, corticosteroids and rituximab Lionet, Arnaud Provôt, François Glowacki, François Frémeaux-Bacchi, Veronique Hazzan, Marc NDT Plus Case Report Complement factor H auto-antibodies (CFH-ab) are a rare cause (6–10%) of atypical haemolytic uraemic syndrome (aHUS). All observations previously described were retrospective and occurred in children or teenagers. We report the first case of aHUS associated with anti-CFH antibodies in an adult patient who was successfully treated by plasma exchange, corticosteroids and rituximab. Oxford University Press 2009-12 2009-08-18 /pmc/articles/PMC4421306/ /pubmed/25984036 http://dx.doi.org/10.1093/ndtplus/sfp109 Text en © The Author 2009. Published by Oxford University Press [on behalf of ERA-EDTA]. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Lionet, Arnaud
Provôt, François
Glowacki, François
Frémeaux-Bacchi, Veronique
Hazzan, Marc
A case of adult atypical haemolytic uraemic syndrome related to anti-factor H autoantibodies successfully treated by plasma exchange, corticosteroids and rituximab
title A case of adult atypical haemolytic uraemic syndrome related to anti-factor H autoantibodies successfully treated by plasma exchange, corticosteroids and rituximab
title_full A case of adult atypical haemolytic uraemic syndrome related to anti-factor H autoantibodies successfully treated by plasma exchange, corticosteroids and rituximab
title_fullStr A case of adult atypical haemolytic uraemic syndrome related to anti-factor H autoantibodies successfully treated by plasma exchange, corticosteroids and rituximab
title_full_unstemmed A case of adult atypical haemolytic uraemic syndrome related to anti-factor H autoantibodies successfully treated by plasma exchange, corticosteroids and rituximab
title_short A case of adult atypical haemolytic uraemic syndrome related to anti-factor H autoantibodies successfully treated by plasma exchange, corticosteroids and rituximab
title_sort case of adult atypical haemolytic uraemic syndrome related to anti-factor h autoantibodies successfully treated by plasma exchange, corticosteroids and rituximab
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421306/
https://www.ncbi.nlm.nih.gov/pubmed/25984036
http://dx.doi.org/10.1093/ndtplus/sfp109
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