A rare cause of nephrotic syndrome in autosomal-dominant polycystic kidney disease

We report the case of a 49-year-old lady who presented with hypertension, breathlessness and malaise. She was thrombocytopenic, with polycystic kidneys on imaging, and was found to have nephrotic syndrome. Serological results were consistent with systemic lupus erythematosus (SLE) and a renal biopsy...

Descripción completa

Detalles Bibliográficos
Autores principales: Wan, Ray K., Kipgen, David, Morris, Scott, Rodger, R. Stuart C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421363/
https://www.ncbi.nlm.nih.gov/pubmed/25949310
http://dx.doi.org/10.1093/ndtplus/sfn197
_version_ 1782369852093104128
author Wan, Ray K.
Kipgen, David
Morris, Scott
Rodger, R. Stuart C.
author_facet Wan, Ray K.
Kipgen, David
Morris, Scott
Rodger, R. Stuart C.
author_sort Wan, Ray K.
collection PubMed
description We report the case of a 49-year-old lady who presented with hypertension, breathlessness and malaise. She was thrombocytopenic, with polycystic kidneys on imaging, and was found to have nephrotic syndrome. Serological results were consistent with systemic lupus erythematosus (SLE) and a renal biopsy confirmed WHO class V lupus nephritis. This is the first reported case of nephrotic syndrome due to lupus nephritis in a patient with autosomal dominant polycystic kidney disease (ADPKD) and underlines the importance of renal biopsy in patients with ADPKD and nephrotic range proteinuria.
format Online
Article
Text
id pubmed-4421363
institution National Center for Biotechnology Information
language English
publishDate 2009
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-44213632015-05-06 A rare cause of nephrotic syndrome in autosomal-dominant polycystic kidney disease Wan, Ray K. Kipgen, David Morris, Scott Rodger, R. Stuart C. NDT Plus Case Report We report the case of a 49-year-old lady who presented with hypertension, breathlessness and malaise. She was thrombocytopenic, with polycystic kidneys on imaging, and was found to have nephrotic syndrome. Serological results were consistent with systemic lupus erythematosus (SLE) and a renal biopsy confirmed WHO class V lupus nephritis. This is the first reported case of nephrotic syndrome due to lupus nephritis in a patient with autosomal dominant polycystic kidney disease (ADPKD) and underlines the importance of renal biopsy in patients with ADPKD and nephrotic range proteinuria. Oxford University Press 2009-04 2008-12-25 /pmc/articles/PMC4421363/ /pubmed/25949310 http://dx.doi.org/10.1093/ndtplus/sfn197 Text en © The Author [2008]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Wan, Ray K.
Kipgen, David
Morris, Scott
Rodger, R. Stuart C.
A rare cause of nephrotic syndrome in autosomal-dominant polycystic kidney disease
title A rare cause of nephrotic syndrome in autosomal-dominant polycystic kidney disease
title_full A rare cause of nephrotic syndrome in autosomal-dominant polycystic kidney disease
title_fullStr A rare cause of nephrotic syndrome in autosomal-dominant polycystic kidney disease
title_full_unstemmed A rare cause of nephrotic syndrome in autosomal-dominant polycystic kidney disease
title_short A rare cause of nephrotic syndrome in autosomal-dominant polycystic kidney disease
title_sort rare cause of nephrotic syndrome in autosomal-dominant polycystic kidney disease
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421363/
https://www.ncbi.nlm.nih.gov/pubmed/25949310
http://dx.doi.org/10.1093/ndtplus/sfn197
work_keys_str_mv AT wanrayk ararecauseofnephroticsyndromeinautosomaldominantpolycystickidneydisease
AT kipgendavid ararecauseofnephroticsyndromeinautosomaldominantpolycystickidneydisease
AT morrisscott ararecauseofnephroticsyndromeinautosomaldominantpolycystickidneydisease
AT rodgerrstuartc ararecauseofnephroticsyndromeinautosomaldominantpolycystickidneydisease
AT wanrayk rarecauseofnephroticsyndromeinautosomaldominantpolycystickidneydisease
AT kipgendavid rarecauseofnephroticsyndromeinautosomaldominantpolycystickidneydisease
AT morrisscott rarecauseofnephroticsyndromeinautosomaldominantpolycystickidneydisease
AT rodgerrstuartc rarecauseofnephroticsyndromeinautosomaldominantpolycystickidneydisease

Ejemplares similares