Collapsing glomerulopathy after hepatitis C pegylated interferon treatment. Recovery of renal function with high-dose steroid treatment

A patient who developed oliguric acute renal failure and nephrotic syndrome within 2 weeks after finishing interferon and ribavirin treatment is reported. At presentation, HCV PCR was negative, and no immunological laboratory test was found altered. A renal biopsy showed collapsing glomerulopathy, a...

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Detalles Bibliográficos
Autores principales: Berdichevski, Roberto H., De Carvalho, Eduardo M., Edelweiss, Maria Isabel, Gonçalves, Luiz Felipe, Manfro, Roberto C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421423/
https://www.ncbi.nlm.nih.gov/pubmed/25949468
http://dx.doi.org/10.1093/ndtplus/sfq155
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author Berdichevski, Roberto H.
De Carvalho, Eduardo M.
Edelweiss, Maria Isabel
Gonçalves, Luiz Felipe
Manfro, Roberto C.
author_facet Berdichevski, Roberto H.
De Carvalho, Eduardo M.
Edelweiss, Maria Isabel
Gonçalves, Luiz Felipe
Manfro, Roberto C.
author_sort Berdichevski, Roberto H.
collection PubMed
description A patient who developed oliguric acute renal failure and nephrotic syndrome within 2 weeks after finishing interferon and ribavirin treatment is reported. At presentation, HCV PCR was negative, and no immunological laboratory test was found altered. A renal biopsy showed collapsing glomerulopathy, and the patient received supportive haemodialysis and high-dose steroids. Twelve days after steroid treatment, renal function started to recover. After 18 weeks, normal renal function and protein/creatinine urinary ratio were achieved and remained normal up to 1-year post-treatment.
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spelling pubmed-44214232015-05-06 Collapsing glomerulopathy after hepatitis C pegylated interferon treatment. Recovery of renal function with high-dose steroid treatment Berdichevski, Roberto H. De Carvalho, Eduardo M. Edelweiss, Maria Isabel Gonçalves, Luiz Felipe Manfro, Roberto C. NDT Plus Case Report A patient who developed oliguric acute renal failure and nephrotic syndrome within 2 weeks after finishing interferon and ribavirin treatment is reported. At presentation, HCV PCR was negative, and no immunological laboratory test was found altered. A renal biopsy showed collapsing glomerulopathy, and the patient received supportive haemodialysis and high-dose steroids. Twelve days after steroid treatment, renal function started to recover. After 18 weeks, normal renal function and protein/creatinine urinary ratio were achieved and remained normal up to 1-year post-treatment. Oxford University Press 2010-12 2010-08-24 /pmc/articles/PMC4421423/ /pubmed/25949468 http://dx.doi.org/10.1093/ndtplus/sfq155 Text en © The Author 2010. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Berdichevski, Roberto H.
De Carvalho, Eduardo M.
Edelweiss, Maria Isabel
Gonçalves, Luiz Felipe
Manfro, Roberto C.
Collapsing glomerulopathy after hepatitis C pegylated interferon treatment. Recovery of renal function with high-dose steroid treatment
title Collapsing glomerulopathy after hepatitis C pegylated interferon treatment. Recovery of renal function with high-dose steroid treatment
title_full Collapsing glomerulopathy after hepatitis C pegylated interferon treatment. Recovery of renal function with high-dose steroid treatment
title_fullStr Collapsing glomerulopathy after hepatitis C pegylated interferon treatment. Recovery of renal function with high-dose steroid treatment
title_full_unstemmed Collapsing glomerulopathy after hepatitis C pegylated interferon treatment. Recovery of renal function with high-dose steroid treatment
title_short Collapsing glomerulopathy after hepatitis C pegylated interferon treatment. Recovery of renal function with high-dose steroid treatment
title_sort collapsing glomerulopathy after hepatitis c pegylated interferon treatment. recovery of renal function with high-dose steroid treatment
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421423/
https://www.ncbi.nlm.nih.gov/pubmed/25949468
http://dx.doi.org/10.1093/ndtplus/sfq155
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