Role of citrate and other methods of anticoagulation in patients with severe liver failure requiring continuous renal replacement therapy

Anticoagulation is required during continuous renal replacement therapy to prevent filter clotting and optimize filter performance. However, anticoagulation may also be associated with serious bleeding complications. Patients with liver failure often suffer from underlying coagulopathy and are espec...

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Detalles Bibliográficos
Autores principales: Bouchard, Josée, Madore, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
In-Depth Clinical Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421492/
https://www.ncbi.nlm.nih.gov/pubmed/25949276
http://dx.doi.org/10.1093/ndtplus/sfn184
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author Bouchard, Josée
Madore, François
author_facet Bouchard, Josée
Madore, François
author_sort Bouchard, Josée
collection PubMed
description Anticoagulation is required during continuous renal replacement therapy to prevent filter clotting and optimize filter performance. However, anticoagulation may also be associated with serious bleeding complications. Patients with liver failure often suffer from underlying coagulopathy and are especially prone to anticoagulation complications. The aim of this review is to present the unique features of patients with hepatic injury in terms of anticoagulation disorders and to analyze data on safety and efficacy of the different anticoagulation methods for liver failure patients undergoing continuous renal replacement therapy.
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spelling pubmed-44214922015-05-06 Role of citrate and other methods of anticoagulation in patients with severe liver failure requiring continuous renal replacement therapy Bouchard, Josée Madore, François NDT Plus In-Depth Clinical Review Anticoagulation is required during continuous renal replacement therapy to prevent filter clotting and optimize filter performance. However, anticoagulation may also be associated with serious bleeding complications. Patients with liver failure often suffer from underlying coagulopathy and are especially prone to anticoagulation complications. The aim of this review is to present the unique features of patients with hepatic injury in terms of anticoagulation disorders and to analyze data on safety and efficacy of the different anticoagulation methods for liver failure patients undergoing continuous renal replacement therapy. Oxford University Press 2009-02 2008-12-09 /pmc/articles/PMC4421492/ /pubmed/25949276 http://dx.doi.org/10.1093/ndtplus/sfn184 Text en © The Author [2008]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle In-Depth Clinical Review
Bouchard, Josée
Madore, François
Role of citrate and other methods of anticoagulation in patients with severe liver failure requiring continuous renal replacement therapy
title Role of citrate and other methods of anticoagulation in patients with severe liver failure requiring continuous renal replacement therapy
title_full Role of citrate and other methods of anticoagulation in patients with severe liver failure requiring continuous renal replacement therapy
title_fullStr Role of citrate and other methods of anticoagulation in patients with severe liver failure requiring continuous renal replacement therapy
title_full_unstemmed Role of citrate and other methods of anticoagulation in patients with severe liver failure requiring continuous renal replacement therapy
title_short Role of citrate and other methods of anticoagulation in patients with severe liver failure requiring continuous renal replacement therapy
title_sort role of citrate and other methods of anticoagulation in patients with severe liver failure requiring continuous renal replacement therapy
topic In-Depth Clinical Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421492/
https://www.ncbi.nlm.nih.gov/pubmed/25949276
http://dx.doi.org/10.1093/ndtplus/sfn184
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