Hypocomplementaemic immune complex tubulointerstitial nephritis

We report a rare cause of rapidly progressive renal failure associated with low complement, positive ANA but negative anti DS-DNA. A renal biopsy demonstrated tubulointerstitial nephritis with positive immunoglobulin staining involving the interstitium and tubular basement membrane but glomerular sp...

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Detalles Bibliográficos
Autores principales: Gupta, Alok, Jothy, Serge, Somerville, Peter, Zaltzman, Jeffrey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421536/
https://www.ncbi.nlm.nih.gov/pubmed/25949412
http://dx.doi.org/10.1093/ndtplus/sfp141
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author Gupta, Alok
Jothy, Serge
Somerville, Peter
Zaltzman, Jeffrey S.
author_facet Gupta, Alok
Jothy, Serge
Somerville, Peter
Zaltzman, Jeffrey S.
author_sort Gupta, Alok
collection PubMed
description We report a rare cause of rapidly progressive renal failure associated with low complement, positive ANA but negative anti DS-DNA. A renal biopsy demonstrated tubulointerstitial nephritis with positive immunoglobulin staining involving the interstitium and tubular basement membrane but glomerular sparing. A review of the literature and differential diagnosis are discussed.
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spelling pubmed-44215362015-05-06 Hypocomplementaemic immune complex tubulointerstitial nephritis Gupta, Alok Jothy, Serge Somerville, Peter Zaltzman, Jeffrey S. NDT Plus Case Report We report a rare cause of rapidly progressive renal failure associated with low complement, positive ANA but negative anti DS-DNA. A renal biopsy demonstrated tubulointerstitial nephritis with positive immunoglobulin staining involving the interstitium and tubular basement membrane but glomerular sparing. A review of the literature and differential diagnosis are discussed. Oxford University Press 2010-02 2009-10-07 /pmc/articles/PMC4421536/ /pubmed/25949412 http://dx.doi.org/10.1093/ndtplus/sfp141 Text en © The Author 2009. Published by Oxford University Press [on behalf of ERA-EDTA]. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Gupta, Alok
Jothy, Serge
Somerville, Peter
Zaltzman, Jeffrey S.
Hypocomplementaemic immune complex tubulointerstitial nephritis
title Hypocomplementaemic immune complex tubulointerstitial nephritis
title_full Hypocomplementaemic immune complex tubulointerstitial nephritis
title_fullStr Hypocomplementaemic immune complex tubulointerstitial nephritis
title_full_unstemmed Hypocomplementaemic immune complex tubulointerstitial nephritis
title_short Hypocomplementaemic immune complex tubulointerstitial nephritis
title_sort hypocomplementaemic immune complex tubulointerstitial nephritis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421536/
https://www.ncbi.nlm.nih.gov/pubmed/25949412
http://dx.doi.org/10.1093/ndtplus/sfp141
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AT somervillepeter hypocomplementaemicimmunecomplextubulointerstitialnephritis
AT zaltzmanjeffreys hypocomplementaemicimmunecomplextubulointerstitialnephritis

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