Ectopic ossification in the cranial dura mater in dialysis patients with secondary hyperparathyroidism

We report the case of a 69-year-old woman with secondary hyperparathyroidism who underwent maintenance haemodialysis therapy for 17 years and who presented with severe dural calcification and right subdural haematoma. Her dura mater displayed a rock barnacle-like appearance, and cerebral superficial...

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Detalles Bibliográficos
Autores principales: Oyama, Yuko, Kazama, Junichiro J., Fukagawa, Mitsutoshi, Arakawa, Yasuaki, Ezuka, Isamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421539/
https://www.ncbi.nlm.nih.gov/pubmed/25949408
http://dx.doi.org/10.1093/ndtplus/sfp115
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author Oyama, Yuko
Kazama, Junichiro J.
Fukagawa, Mitsutoshi
Arakawa, Yasuaki
Ezuka, Isamu
author_facet Oyama, Yuko
Kazama, Junichiro J.
Fukagawa, Mitsutoshi
Arakawa, Yasuaki
Ezuka, Isamu
author_sort Oyama, Yuko
collection PubMed
description We report the case of a 69-year-old woman with secondary hyperparathyroidism who underwent maintenance haemodialysis therapy for 17 years and who presented with severe dural calcification and right subdural haematoma. Her dura mater displayed a rock barnacle-like appearance, and cerebral superficial arteries adhered to the sclerotic lesions. On the microscopic observation, calcified tissue with a clear lamellar structure and osteopontin immunoreactivity was observed. Tartrate-resistant acid phosphatase immunoreactive polynucleated giant cells infiltrated around the tissue. Such morphological properties are specific to the calcified tissue formed through a bone formation-like mechanism that is often observed in arterial media in patients with chronic kidney disease.
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spelling pubmed-44215392015-05-06 Ectopic ossification in the cranial dura mater in dialysis patients with secondary hyperparathyroidism Oyama, Yuko Kazama, Junichiro J. Fukagawa, Mitsutoshi Arakawa, Yasuaki Ezuka, Isamu NDT Plus Case Report We report the case of a 69-year-old woman with secondary hyperparathyroidism who underwent maintenance haemodialysis therapy for 17 years and who presented with severe dural calcification and right subdural haematoma. Her dura mater displayed a rock barnacle-like appearance, and cerebral superficial arteries adhered to the sclerotic lesions. On the microscopic observation, calcified tissue with a clear lamellar structure and osteopontin immunoreactivity was observed. Tartrate-resistant acid phosphatase immunoreactive polynucleated giant cells infiltrated around the tissue. Such morphological properties are specific to the calcified tissue formed through a bone formation-like mechanism that is often observed in arterial media in patients with chronic kidney disease. Oxford University Press 2010-02 2009-09-09 /pmc/articles/PMC4421539/ /pubmed/25949408 http://dx.doi.org/10.1093/ndtplus/sfp115 Text en © The Author 2009. Published by Oxford University Press [on behalf of ERA-EDTA]. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Oyama, Yuko
Kazama, Junichiro J.
Fukagawa, Mitsutoshi
Arakawa, Yasuaki
Ezuka, Isamu
Ectopic ossification in the cranial dura mater in dialysis patients with secondary hyperparathyroidism
title Ectopic ossification in the cranial dura mater in dialysis patients with secondary hyperparathyroidism
title_full Ectopic ossification in the cranial dura mater in dialysis patients with secondary hyperparathyroidism
title_fullStr Ectopic ossification in the cranial dura mater in dialysis patients with secondary hyperparathyroidism
title_full_unstemmed Ectopic ossification in the cranial dura mater in dialysis patients with secondary hyperparathyroidism
title_short Ectopic ossification in the cranial dura mater in dialysis patients with secondary hyperparathyroidism
title_sort ectopic ossification in the cranial dura mater in dialysis patients with secondary hyperparathyroidism
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421539/
https://www.ncbi.nlm.nih.gov/pubmed/25949408
http://dx.doi.org/10.1093/ndtplus/sfp115
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