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Ranolazine can markedly increase tacrolimus blood levels

We report the case of a renal transplant patient on tacrolimus who developed a fully reversible renal failure and a doubling in serum tacrolimus closely associated with initiation of ranolazine (Ranexa) treatment, a new anti-angina drug recently introduced in Europe.

Detalles Bibliográficos
Autores principales: Seck, Sidy, Bellantoni, Marianna, Zoccali, Carmine, Enia, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421639/
https://www.ncbi.nlm.nih.gov/pubmed/25984101
http://dx.doi.org/10.1093/ndtplus/sfq180
Descripción
Sumario:We report the case of a renal transplant patient on tacrolimus who developed a fully reversible renal failure and a doubling in serum tacrolimus closely associated with initiation of ranolazine (Ranexa) treatment, a new anti-angina drug recently introduced in Europe.