Successful renal transplantation in Muckle–Wells syndrome treated with anti-IL-1β-monoclonal antibody

We report the first case of a 32-year-old woman with Muckle–Wells syndrome and biopsy-proven systemic AA amyloidosis and end-stage renal disease. She was treated with canakinumab 150 mg subcutaneously every 8 weeks and underwent renal transplantation. Fourteen months after renal transplanation, the...

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Autores principales: Kortus-Götze, Birgit, Hoyer, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
II. Clinical Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421672/
https://www.ncbi.nlm.nih.gov/pubmed/25984207
http://dx.doi.org/10.1093/ndtplus/sfr118
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author Kortus-Götze, Birgit
Hoyer, Joachim
author_facet Kortus-Götze, Birgit
Hoyer, Joachim
author_sort Kortus-Götze, Birgit
collection PubMed
description We report the first case of a 32-year-old woman with Muckle–Wells syndrome and biopsy-proven systemic AA amyloidosis and end-stage renal disease. She was treated with canakinumab 150 mg subcutaneously every 8 weeks and underwent renal transplantation. Fourteen months after renal transplanation, the patient had no flares of Muckle–Wells syndrome and no evidence of amyloidosis in the renal transplant under an excellent graft function and therapy with canakinumab.
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spelling pubmed-44216722015-05-15 Successful renal transplantation in Muckle–Wells syndrome treated with anti-IL-1β-monoclonal antibody Kortus-Götze, Birgit Hoyer, Joachim NDT Plus II. Clinical Reports We report the first case of a 32-year-old woman with Muckle–Wells syndrome and biopsy-proven systemic AA amyloidosis and end-stage renal disease. She was treated with canakinumab 150 mg subcutaneously every 8 weeks and underwent renal transplantation. Fourteen months after renal transplanation, the patient had no flares of Muckle–Wells syndrome and no evidence of amyloidosis in the renal transplant under an excellent graft function and therapy with canakinumab. Oxford University Press 2011-12 /pmc/articles/PMC4421672/ /pubmed/25984207 http://dx.doi.org/10.1093/ndtplus/sfr118 Text en © The Author 2011. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle II. Clinical Reports
Kortus-Götze, Birgit
Hoyer, Joachim
Successful renal transplantation in Muckle–Wells syndrome treated with anti-IL-1β-monoclonal antibody
title Successful renal transplantation in Muckle–Wells syndrome treated with anti-IL-1β-monoclonal antibody
title_full Successful renal transplantation in Muckle–Wells syndrome treated with anti-IL-1β-monoclonal antibody
title_fullStr Successful renal transplantation in Muckle–Wells syndrome treated with anti-IL-1β-monoclonal antibody
title_full_unstemmed Successful renal transplantation in Muckle–Wells syndrome treated with anti-IL-1β-monoclonal antibody
title_short Successful renal transplantation in Muckle–Wells syndrome treated with anti-IL-1β-monoclonal antibody
title_sort successful renal transplantation in muckle–wells syndrome treated with anti-il-1β-monoclonal antibody
topic II. Clinical Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421672/
https://www.ncbi.nlm.nih.gov/pubmed/25984207
http://dx.doi.org/10.1093/ndtplus/sfr118
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