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Progressive renal failure in a patient with lung adenocarcinoma

We present an interesting case of a young female smoker who was hospitalized for shortness of breath and acute renal insufficiency (serum creatinine = 2.8 mg/dL). Few weeks prior to admission, she was discovered to have a right lung mass, and a biopsy confirmed lung adenocarcinoma. Her work-up revea...

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Autores principales: Agrawal, Varun, Ye, Jiuming, McCann, John, Hehn, Boyd, Freeman, Jonathan, Allen, Steve, Braden, Gregory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421709/
https://www.ncbi.nlm.nih.gov/pubmed/25984054
http://dx.doi.org/10.1093/ndtplus/sfq091
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author Agrawal, Varun
Ye, Jiuming
McCann, John
Hehn, Boyd
Freeman, Jonathan
Allen, Steve
Braden, Gregory
author_facet Agrawal, Varun
Ye, Jiuming
McCann, John
Hehn, Boyd
Freeman, Jonathan
Allen, Steve
Braden, Gregory
author_sort Agrawal, Varun
collection PubMed
description We present an interesting case of a young female smoker who was hospitalized for shortness of breath and acute renal insufficiency (serum creatinine = 2.8 mg/dL). Few weeks prior to admission, she was discovered to have a right lung mass, and a biopsy confirmed lung adenocarcinoma. Her work-up revealed an unremarkable urinalysis quantitatively and on microscopic analysis. Renal ultrasound demonstrated enlarged bilateral unobstructed kidneys, while a nuclear scan showed increased activity in both kidneys. Renal biopsy established the diagnosis of diffuse metastatic infiltration of both kidneys from primary lung adenocarcinoma. Her renal function worsened despite initiation of chemotherapy. Carcinomatous infiltration of the kidneys is an extremely rare and unusual cause of renal injury that must be suspected in a patient with cancer and large kidneys.
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spelling pubmed-44217092015-05-15 Progressive renal failure in a patient with lung adenocarcinoma Agrawal, Varun Ye, Jiuming McCann, John Hehn, Boyd Freeman, Jonathan Allen, Steve Braden, Gregory NDT Plus Case Report We present an interesting case of a young female smoker who was hospitalized for shortness of breath and acute renal insufficiency (serum creatinine = 2.8 mg/dL). Few weeks prior to admission, she was discovered to have a right lung mass, and a biopsy confirmed lung adenocarcinoma. Her work-up revealed an unremarkable urinalysis quantitatively and on microscopic analysis. Renal ultrasound demonstrated enlarged bilateral unobstructed kidneys, while a nuclear scan showed increased activity in both kidneys. Renal biopsy established the diagnosis of diffuse metastatic infiltration of both kidneys from primary lung adenocarcinoma. Her renal function worsened despite initiation of chemotherapy. Carcinomatous infiltration of the kidneys is an extremely rare and unusual cause of renal injury that must be suspected in a patient with cancer and large kidneys. Oxford University Press 2010-10 2010-05-20 /pmc/articles/PMC4421709/ /pubmed/25984054 http://dx.doi.org/10.1093/ndtplus/sfq091 Text en © The Author 2010. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Agrawal, Varun
Ye, Jiuming
McCann, John
Hehn, Boyd
Freeman, Jonathan
Allen, Steve
Braden, Gregory
Progressive renal failure in a patient with lung adenocarcinoma
title Progressive renal failure in a patient with lung adenocarcinoma
title_full Progressive renal failure in a patient with lung adenocarcinoma
title_fullStr Progressive renal failure in a patient with lung adenocarcinoma
title_full_unstemmed Progressive renal failure in a patient with lung adenocarcinoma
title_short Progressive renal failure in a patient with lung adenocarcinoma
title_sort progressive renal failure in a patient with lung adenocarcinoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421709/
https://www.ncbi.nlm.nih.gov/pubmed/25984054
http://dx.doi.org/10.1093/ndtplus/sfq091
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