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Progressive renal failure in a patient with lung adenocarcinoma
We present an interesting case of a young female smoker who was hospitalized for shortness of breath and acute renal insufficiency (serum creatinine = 2.8 mg/dL). Few weeks prior to admission, she was discovered to have a right lung mass, and a biopsy confirmed lung adenocarcinoma. Her work-up revea...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421709/ https://www.ncbi.nlm.nih.gov/pubmed/25984054 http://dx.doi.org/10.1093/ndtplus/sfq091 |
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author | Agrawal, Varun Ye, Jiuming McCann, John Hehn, Boyd Freeman, Jonathan Allen, Steve Braden, Gregory |
author_facet | Agrawal, Varun Ye, Jiuming McCann, John Hehn, Boyd Freeman, Jonathan Allen, Steve Braden, Gregory |
author_sort | Agrawal, Varun |
collection | PubMed |
description | We present an interesting case of a young female smoker who was hospitalized for shortness of breath and acute renal insufficiency (serum creatinine = 2.8 mg/dL). Few weeks prior to admission, she was discovered to have a right lung mass, and a biopsy confirmed lung adenocarcinoma. Her work-up revealed an unremarkable urinalysis quantitatively and on microscopic analysis. Renal ultrasound demonstrated enlarged bilateral unobstructed kidneys, while a nuclear scan showed increased activity in both kidneys. Renal biopsy established the diagnosis of diffuse metastatic infiltration of both kidneys from primary lung adenocarcinoma. Her renal function worsened despite initiation of chemotherapy. Carcinomatous infiltration of the kidneys is an extremely rare and unusual cause of renal injury that must be suspected in a patient with cancer and large kidneys. |
format | Online Article Text |
id | pubmed-4421709 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-44217092015-05-15 Progressive renal failure in a patient with lung adenocarcinoma Agrawal, Varun Ye, Jiuming McCann, John Hehn, Boyd Freeman, Jonathan Allen, Steve Braden, Gregory NDT Plus Case Report We present an interesting case of a young female smoker who was hospitalized for shortness of breath and acute renal insufficiency (serum creatinine = 2.8 mg/dL). Few weeks prior to admission, she was discovered to have a right lung mass, and a biopsy confirmed lung adenocarcinoma. Her work-up revealed an unremarkable urinalysis quantitatively and on microscopic analysis. Renal ultrasound demonstrated enlarged bilateral unobstructed kidneys, while a nuclear scan showed increased activity in both kidneys. Renal biopsy established the diagnosis of diffuse metastatic infiltration of both kidneys from primary lung adenocarcinoma. Her renal function worsened despite initiation of chemotherapy. Carcinomatous infiltration of the kidneys is an extremely rare and unusual cause of renal injury that must be suspected in a patient with cancer and large kidneys. Oxford University Press 2010-10 2010-05-20 /pmc/articles/PMC4421709/ /pubmed/25984054 http://dx.doi.org/10.1093/ndtplus/sfq091 Text en © The Author 2010. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Case Report Agrawal, Varun Ye, Jiuming McCann, John Hehn, Boyd Freeman, Jonathan Allen, Steve Braden, Gregory Progressive renal failure in a patient with lung adenocarcinoma |
title | Progressive renal failure in a patient with lung adenocarcinoma |
title_full | Progressive renal failure in a patient with lung adenocarcinoma |
title_fullStr | Progressive renal failure in a patient with lung adenocarcinoma |
title_full_unstemmed | Progressive renal failure in a patient with lung adenocarcinoma |
title_short | Progressive renal failure in a patient with lung adenocarcinoma |
title_sort | progressive renal failure in a patient with lung adenocarcinoma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421709/ https://www.ncbi.nlm.nih.gov/pubmed/25984054 http://dx.doi.org/10.1093/ndtplus/sfq091 |
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