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Clathrin inhibitor Pitstop-2 disrupts the nuclear pore complex permeability barrier

Existence of a selective nucleocytoplasmic permeability barrier is attributed to Phenylalanine-Glycine rich proteins (FG-nups) within the central channel of the nuclear pore complex (NPC). Limited understanding of the FG-nup structural arrangement hinders development of strategies directed at disrup...

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Detalles Bibliográficos
Autores principales:	Liashkovich, Ivan, Pasrednik, Dzmitry, Prystopiuk, Valeria, Rosso, Gonzalo, Oberleithner, Hans, Shahin, Victor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421796/ https://www.ncbi.nlm.nih.gov/pubmed/25944393 http://dx.doi.org/10.1038/srep09994

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