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Acetylation of MAT IIα represses tumour cell growth and is decreased in human hepatocellular cancer

Metabolic alteration is a hallmark of cancer. Dysregulation of methionine metabolism is implicated in human liver cancer. Methionine adenosyltransferase IIα (MAT IIα) is a key enzyme in the methionine cycle, catalysing the production of S-adenosylmethionine (SAM), a key methyl donor in cellular proc...

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Detalles Bibliográficos
Autores principales:	Yang, Hong-Bin, Xu, Ying-Ying, Zhao, Xiang-Ning, Zou, Shao-Wu, Zhang, Ye, Zhang, Min, Li, Jin-Tao, Ren, Feng, Wang, Li-Ying, Lei, Qun-Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Pub. Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421817/ https://www.ncbi.nlm.nih.gov/pubmed/25925782 http://dx.doi.org/10.1038/ncomms7973

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