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Report of a successful ongoing pregnancy as a result of IMSI with assisted oocyte activation

We report a successful ongoing pregnancy obtained in a case of total globozoospermia after intracytoplasmic morphologically selected sperm injection (IMSI) with oocyte activation. The first semen analysis on investigation showed partial globozoospermia. However, under high magnification assessment a...

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Detalles Bibliográficos
Autores principales: Doroftei, Bogdan, Zlei, Mihaela, Simionescu, Gabriela, Maftei, Radu, Cumpata, Simona, Emerson, Geraldine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421912/
https://www.ncbi.nlm.nih.gov/pubmed/25935518
http://dx.doi.org/10.1186/s12978-015-0031-x
Descripción
Sumario:We report a successful ongoing pregnancy obtained in a case of total globozoospermia after intracytoplasmic morphologically selected sperm injection (IMSI) with oocyte activation. The first semen analysis on investigation showed partial globozoospermia. However, under high magnification assessment at oocyte retrieval only round headed sperm were observed. Considering the high risk of a complete failure to fertilize from IMSI the couple gave written informed consent to the use of oocyte activation media post IMSI. One embryo fertilized, developed to a hatching blastocyst and was transferred resulting in an ongoing pregnancy. This successful outcome shows the use of IMSI is useful in the evaluation of total globozooozpermia and therefore aids in the justification of the use of oocyte activation media. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12978-015-0031-x) contains supplementary material, which is available to authorized users.