Report of a successful ongoing pregnancy as a result of IMSI with assisted oocyte activation

We report a successful ongoing pregnancy obtained in a case of total globozoospermia after intracytoplasmic morphologically selected sperm injection (IMSI) with oocyte activation. The first semen analysis on investigation showed partial globozoospermia. However, under high magnification assessment a...

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Detalles Bibliográficos
Autores principales: Doroftei, Bogdan, Zlei, Mihaela, Simionescu, Gabriela, Maftei, Radu, Cumpata, Simona, Emerson, Geraldine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421912/
https://www.ncbi.nlm.nih.gov/pubmed/25935518
http://dx.doi.org/10.1186/s12978-015-0031-x
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author Doroftei, Bogdan
Zlei, Mihaela
Simionescu, Gabriela
Maftei, Radu
Cumpata, Simona
Emerson, Geraldine
author_facet Doroftei, Bogdan
Zlei, Mihaela
Simionescu, Gabriela
Maftei, Radu
Cumpata, Simona
Emerson, Geraldine
author_sort Doroftei, Bogdan
collection PubMed
description We report a successful ongoing pregnancy obtained in a case of total globozoospermia after intracytoplasmic morphologically selected sperm injection (IMSI) with oocyte activation. The first semen analysis on investigation showed partial globozoospermia. However, under high magnification assessment at oocyte retrieval only round headed sperm were observed. Considering the high risk of a complete failure to fertilize from IMSI the couple gave written informed consent to the use of oocyte activation media post IMSI. One embryo fertilized, developed to a hatching blastocyst and was transferred resulting in an ongoing pregnancy. This successful outcome shows the use of IMSI is useful in the evaluation of total globozooozpermia and therefore aids in the justification of the use of oocyte activation media. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12978-015-0031-x) contains supplementary material, which is available to authorized users.
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spelling pubmed-44219122015-05-07 Report of a successful ongoing pregnancy as a result of IMSI with assisted oocyte activation Doroftei, Bogdan Zlei, Mihaela Simionescu, Gabriela Maftei, Radu Cumpata, Simona Emerson, Geraldine Reprod Health Case Report We report a successful ongoing pregnancy obtained in a case of total globozoospermia after intracytoplasmic morphologically selected sperm injection (IMSI) with oocyte activation. The first semen analysis on investigation showed partial globozoospermia. However, under high magnification assessment at oocyte retrieval only round headed sperm were observed. Considering the high risk of a complete failure to fertilize from IMSI the couple gave written informed consent to the use of oocyte activation media post IMSI. One embryo fertilized, developed to a hatching blastocyst and was transferred resulting in an ongoing pregnancy. This successful outcome shows the use of IMSI is useful in the evaluation of total globozooozpermia and therefore aids in the justification of the use of oocyte activation media. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12978-015-0031-x) contains supplementary material, which is available to authorized users. BioMed Central 2015-05-03 /pmc/articles/PMC4421912/ /pubmed/25935518 http://dx.doi.org/10.1186/s12978-015-0031-x Text en © Doroftei et al.; licensee BioMed Central. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Doroftei, Bogdan
Zlei, Mihaela
Simionescu, Gabriela
Maftei, Radu
Cumpata, Simona
Emerson, Geraldine
Report of a successful ongoing pregnancy as a result of IMSI with assisted oocyte activation
title Report of a successful ongoing pregnancy as a result of IMSI with assisted oocyte activation
title_full Report of a successful ongoing pregnancy as a result of IMSI with assisted oocyte activation
title_fullStr Report of a successful ongoing pregnancy as a result of IMSI with assisted oocyte activation
title_full_unstemmed Report of a successful ongoing pregnancy as a result of IMSI with assisted oocyte activation
title_short Report of a successful ongoing pregnancy as a result of IMSI with assisted oocyte activation
title_sort report of a successful ongoing pregnancy as a result of imsi with assisted oocyte activation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421912/
https://www.ncbi.nlm.nih.gov/pubmed/25935518
http://dx.doi.org/10.1186/s12978-015-0031-x
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