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Rhabdoid meningioma lacking malignant features: Report of a rare case with review of literature

We reported a case of meningioma with rhabdoid morphology but lacking histological features of malignancy in arising from the spinal cord in a 28-year-old male. The tumor showed light microscopic, immunohistochemical evidence of meningothelial differentiation together with diffuse areas exhibiting r...

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Detalles Bibliográficos
Autores principales: Mardi, Kavita, Thakur, R. C., Biswas, Biswajit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421966/
https://www.ncbi.nlm.nih.gov/pubmed/25972960
http://dx.doi.org/10.4103/1793-5482.153499
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author Mardi, Kavita
Thakur, R. C.
Biswas, Biswajit
author_facet Mardi, Kavita
Thakur, R. C.
Biswas, Biswajit
author_sort Mardi, Kavita
collection PubMed
description We reported a case of meningioma with rhabdoid morphology but lacking histological features of malignancy in arising from the spinal cord in a 28-year-old male. The tumor showed light microscopic, immunohistochemical evidence of meningothelial differentiation together with diffuse areas exhibiting rhabdoid morphology. The rhabdoid areas were characterized by cells with large cytoplasmic eosinophilic inclusions and eccentric nuclei. Unlike most cases reported in the literature, this case lacked significant mitotic activity and other atypical features. The diagnostic and prognostic significance of this tumor entity is discussed along with a review of the literature.
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spelling pubmed-44219662015-05-13 Rhabdoid meningioma lacking malignant features: Report of a rare case with review of literature Mardi, Kavita Thakur, R. C. Biswas, Biswajit Asian J Neurosurg Case Report We reported a case of meningioma with rhabdoid morphology but lacking histological features of malignancy in arising from the spinal cord in a 28-year-old male. The tumor showed light microscopic, immunohistochemical evidence of meningothelial differentiation together with diffuse areas exhibiting rhabdoid morphology. The rhabdoid areas were characterized by cells with large cytoplasmic eosinophilic inclusions and eccentric nuclei. Unlike most cases reported in the literature, this case lacked significant mitotic activity and other atypical features. The diagnostic and prognostic significance of this tumor entity is discussed along with a review of the literature. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4421966/ /pubmed/25972960 http://dx.doi.org/10.4103/1793-5482.153499 Text en Copyright: © Asian Journal of Neurosurgery http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Mardi, Kavita
Thakur, R. C.
Biswas, Biswajit
Rhabdoid meningioma lacking malignant features: Report of a rare case with review of literature
title Rhabdoid meningioma lacking malignant features: Report of a rare case with review of literature
title_full Rhabdoid meningioma lacking malignant features: Report of a rare case with review of literature
title_fullStr Rhabdoid meningioma lacking malignant features: Report of a rare case with review of literature
title_full_unstemmed Rhabdoid meningioma lacking malignant features: Report of a rare case with review of literature
title_short Rhabdoid meningioma lacking malignant features: Report of a rare case with review of literature
title_sort rhabdoid meningioma lacking malignant features: report of a rare case with review of literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421966/
https://www.ncbi.nlm.nih.gov/pubmed/25972960
http://dx.doi.org/10.4103/1793-5482.153499
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