Cargando…
Rhabdoid meningioma lacking malignant features: Report of a rare case with review of literature
We reported a case of meningioma with rhabdoid morphology but lacking histological features of malignancy in arising from the spinal cord in a 28-year-old male. The tumor showed light microscopic, immunohistochemical evidence of meningothelial differentiation together with diffuse areas exhibiting r...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421966/ https://www.ncbi.nlm.nih.gov/pubmed/25972960 http://dx.doi.org/10.4103/1793-5482.153499 |
_version_ | 1782369983427248128 |
---|---|
author | Mardi, Kavita Thakur, R. C. Biswas, Biswajit |
author_facet | Mardi, Kavita Thakur, R. C. Biswas, Biswajit |
author_sort | Mardi, Kavita |
collection | PubMed |
description | We reported a case of meningioma with rhabdoid morphology but lacking histological features of malignancy in arising from the spinal cord in a 28-year-old male. The tumor showed light microscopic, immunohistochemical evidence of meningothelial differentiation together with diffuse areas exhibiting rhabdoid morphology. The rhabdoid areas were characterized by cells with large cytoplasmic eosinophilic inclusions and eccentric nuclei. Unlike most cases reported in the literature, this case lacked significant mitotic activity and other atypical features. The diagnostic and prognostic significance of this tumor entity is discussed along with a review of the literature. |
format | Online Article Text |
id | pubmed-4421966 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-44219662015-05-13 Rhabdoid meningioma lacking malignant features: Report of a rare case with review of literature Mardi, Kavita Thakur, R. C. Biswas, Biswajit Asian J Neurosurg Case Report We reported a case of meningioma with rhabdoid morphology but lacking histological features of malignancy in arising from the spinal cord in a 28-year-old male. The tumor showed light microscopic, immunohistochemical evidence of meningothelial differentiation together with diffuse areas exhibiting rhabdoid morphology. The rhabdoid areas were characterized by cells with large cytoplasmic eosinophilic inclusions and eccentric nuclei. Unlike most cases reported in the literature, this case lacked significant mitotic activity and other atypical features. The diagnostic and prognostic significance of this tumor entity is discussed along with a review of the literature. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4421966/ /pubmed/25972960 http://dx.doi.org/10.4103/1793-5482.153499 Text en Copyright: © Asian Journal of Neurosurgery http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Mardi, Kavita Thakur, R. C. Biswas, Biswajit Rhabdoid meningioma lacking malignant features: Report of a rare case with review of literature |
title | Rhabdoid meningioma lacking malignant features: Report of a rare case with review of literature |
title_full | Rhabdoid meningioma lacking malignant features: Report of a rare case with review of literature |
title_fullStr | Rhabdoid meningioma lacking malignant features: Report of a rare case with review of literature |
title_full_unstemmed | Rhabdoid meningioma lacking malignant features: Report of a rare case with review of literature |
title_short | Rhabdoid meningioma lacking malignant features: Report of a rare case with review of literature |
title_sort | rhabdoid meningioma lacking malignant features: report of a rare case with review of literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421966/ https://www.ncbi.nlm.nih.gov/pubmed/25972960 http://dx.doi.org/10.4103/1793-5482.153499 |
work_keys_str_mv | AT mardikavita rhabdoidmeningiomalackingmalignantfeaturesreportofararecasewithreviewofliterature AT thakurrc rhabdoidmeningiomalackingmalignantfeaturesreportofararecasewithreviewofliterature AT biswasbiswajit rhabdoidmeningiomalackingmalignantfeaturesreportofararecasewithreviewofliterature |