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Aneuploid proliferation defects in yeast are not driven by copy number changes of a few dosage-sensitive genes
Aneuploidy—the gain or loss of one or more whole chromosome—typically has an adverse impact on organismal fitness, manifest in conditions such as Down syndrome. A central question is whether aneuploid phenotypes are the consequence of copy number changes of a few especially harmful genes that may be...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421978/ https://www.ncbi.nlm.nih.gov/pubmed/25934502 http://dx.doi.org/10.1101/gad.261743.115 |