Loss of the RNA polymerase III repressor MAF1 confers obesity resistance

MAF1 is a global repressor of RNA polymerase III transcription that regulates the expression of highly abundant noncoding RNAs in response to nutrient availability and cellular stress. Thus, MAF1 function is thought to be important for metabolic economy. Here we show that a whole-body knockout of Ma...

Descripción completa

Detalles Bibliográficos
Autores principales: Bonhoure, Nicolas, Byrnes, Ashlee, Moir, Robyn D., Hodroj, Wassim, Preitner, Frédéric, Praz, Viviane, Marcelin, Genevieve, Chua, Streamson C., Martinez-Lopez, Nuria, Singh, Rajat, Moullan, Norman, Auwerx, Johan, Willemin, Gilles, Shah, Hardik, Hartil, Kirsten, Vaitheesvaran, Bhavapriya, Kurland, Irwin, Hernandez, Nouria, Willis, Ian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421982/
https://www.ncbi.nlm.nih.gov/pubmed/25934505
http://dx.doi.org/10.1101/gad.258350.115

Ejemplares similares

Ejemplares similares