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Genome-wide analysis of human global and transcription-coupled excision repair of UV damage at single-nucleotide resolution

We developed a method for genome-wide mapping of DNA excision repair named XR-seq (excision repair sequencing). Human nucleotide excision repair generates two incisions surrounding the site of damage, creating an ∼30-mer. In XR-seq, this fragment is isolated and subjected to high-throughput sequenci...

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Detalles Bibliográficos
Autores principales:	Hu, Jinchuan, Adar, Sheera, Selby, Christopher P., Lieb, Jason D., Sancar, Aziz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421983/ https://www.ncbi.nlm.nih.gov/pubmed/25934506 http://dx.doi.org/10.1101/gad.261271.115

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