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Wilms’ tumor gene 1 regulates p63 and promotes cell proliferation in squamous cell carcinoma of the head and neck

BACKGROUND: Wilms’ tumor gene 1 (WT1) can act as a suppressor or activator of tumourigenesis in different types of human malignancies. The role of WT1 in squamous cell carcinoma of the head and neck (SCCHN) is not clear. Overexpression of WT1 has been reported in SCCHN, suggesting a possible oncogen...

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Detalles Bibliográficos
Autores principales: Li, Xingru, Ottosson, Sofia, Wang, Sihan, Jernberg, Emma, Boldrup, Linda, Gu, Xiaolian, Nylander, Karin, Li, Aihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421988/
https://www.ncbi.nlm.nih.gov/pubmed/25929687
http://dx.doi.org/10.1186/s12885-015-1356-0