Acute intracerebral treatment with amyloid-beta (1–42) alters the profile of neuronal oscillations that accompany LTP induction and results in impaired LTP in freely behaving rats

Accumulation of amyloid plaques comprises one of the major hallmarks of Alzheimer’s disease (AD). In rodents, acute treatment with amyloid-beta (Aβ; 1–42) elicits immediate debilitating effects on hippocampal long-term potentiation (LTP). Whereas LTP contributes to synaptic information storage, info...

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Detalles Bibliográficos
Autores principales: Kalweit, Alexander Nikolai, Yang, Honghong, Colitti-Klausnitzer, Jens, Fülöp, Livia, Bozsó, Zsolt, Penke, Botond, Manahan-Vaughan, Denise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422036/
https://www.ncbi.nlm.nih.gov/pubmed/25999827
http://dx.doi.org/10.3389/fnbeh.2015.00103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422036/
https://www.ncbi.nlm.nih.gov/pubmed/25999827
http://dx.doi.org/10.3389/fnbeh.2015.00103

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