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Ubiquitylation, neddylation and the DNA damage response

Failure of accurate DNA damage sensing and repair mechanisms manifests as a variety of human diseases, including neurodegenerative disorders, immunodeficiency, infertility and cancer. The accuracy and efficiency of DNA damage detection and repair, collectively termed the DNA damage response (DDR), r...

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Detalles Bibliográficos
Autores principales: Brown, Jessica S., Jackson, Stephen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422126/
https://www.ncbi.nlm.nih.gov/pubmed/25833379
http://dx.doi.org/10.1098/rsob.150018