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Quantifying conformational changes in GPCRs: glimpse of a common functional mechanism
BACKGROUND: G-protein-coupled receptors (GPCRs) are important drug targets and a better understanding of their molecular mechanisms would be desirable. The crystallization rate of GPCRs has accelerated in recent years as techniques have become more sophisticated, particularly with respect to Class A...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422131/ https://www.ncbi.nlm.nih.gov/pubmed/25902715 http://dx.doi.org/10.1186/s12859-015-0567-3 |