Cargando…

Genome-wide amplification of proviral sequences reveals new polymorphic HERV-K(HML-2) proviruses in humans and chimpanzees that are absent from genome assemblies

BACKGROUND: To date, the human population census of proviruses of the Betaretrovirus–like human endogenous retroviral (HERV-K) (HML-2) family has been compiled from a limited number of complete genomes, making it certain that rare polymorphic loci are under-represented and are yet to be described. R...

Descripción completa

Detalles Bibliográficos
Autores principales:	Macfarlane, Catriona M, Badge, Richard M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422153/ https://www.ncbi.nlm.nih.gov/pubmed/25927962 http://dx.doi.org/10.1186/s12977-015-0162-8

Ejemplares similares

Widespread expression of the ancient HERV-K (HML-2) provirus group in normal human tissues
por: Burn, Aidan, et al.
Publicado: (2022)

Differential Expression of HERV-K (HML-2) Proviruses in Cells and Virions of the Teratocarcinoma Cell Line Tera-1
por: Bhardwaj, Neeru, et al.
Publicado: (2015)

Effect of aging on the transcriptomic changes associated with the expression of the HERV-K (HML-2) provirus at 1q22
por: Autio, Arttu, et al.
Publicado: (2020)

Promoter expression of HERV-K (HML-2) provirus-derived sequences is related to LTR sequence variation and polymorphic transcription factor binding sites
por: Montesion, Meagan, et al.
Publicado: (2018)

Identification of a novel HERV-K(HML10): comprehensive characterization and comparative analysis in non-human primates provide insights about HML10 proviruses structure and diffusion
por: Grandi, Nicole, et al.
Publicado: (2017)

Comprehensive identification and characterization of the HERV-K (HML-9) group in the human genome
por: Jia, Lei, et al.
Publicado: (2022)

Identification, comprehensive characterization, and comparative genomics of the HERV-K(HML8) integrations in the human genome
por: Scognamiglio, Sante, et al.
Publicado: (2022)

Ancient Adversary – HERV-K (HML-2) in Cancer
por: Dervan, Eoin, et al.
Publicado: (2021)

HERV-K(HML-2), the Best Preserved Family of HERVs: Endogenization, Expression, and Implications in Health and Disease
por: Hohn, Oliver, et al.
Publicado: (2013)

Identification, characterization, and comparative genomic distribution of the HERV-K (HML-2) group of human endogenous retroviruses
por: Subramanian, Ravi P, et al.
Publicado: (2011)

Transcriptional profiling of HERV-K(HML-2) in amyotrophic lateral sclerosis and potential implications for expression of HML-2 proteins
por: Mayer, Jens, et al.
Publicado: (2018)

HERV-K(HML7) Integrations in the Human Genome: Comprehensive Characterization and Comparative Analysis in Non-Human Primates
por: Grandi, Nicole, et al.
Publicado: (2021)

Comprehensive Analysis of HERV Transcriptome in HIV+ Cells: Absence of HML2 Activation and General Downregulation of Individual HERV Loci
por: Grandi, Nicole, et al.
Publicado: (2020)

Identification of differentially expressed HERV-K(HML-2) loci in colorectal cancer
por: Kang, Qian, et al.
Publicado: (2023)

Exploring HERV-K (HML-2) Influence in Cancer and Prospects for Therapeutic Interventions
por: Costa, Bárbara, et al.
Publicado: (2023)

Anti-HERV-K (HML-2) capsid antibody responses in HIV elite controllers
por: de Mulder, Miguel, et al.
Publicado: (2017)

Not all viruses cause disease: HERV-K(HML-2) in healthy human tissues
por: Srinivasachar Badarinarayan, Smitha, et al.
Publicado: (2022)

HIV-1 Rev interacts with HERV-K RcREs present in the human genome and promotes export of unspliced HERV-K proviral RNA
por: Gray, Laurie R., et al.
Publicado: (2019)

Intragenic proviral elements support transcription of defective HIV-1 proviruses
por: Kuniholm, Jeffrey, et al.
Publicado: (2021)

CMV-Promoter Driven Codon-Optimized Expression Alters the Assembly Type and Morphology of a Reconstituted HERV-K(HML-2)
por: Hohn, Oliver, et al.
Publicado: (2014)

Transcriptional Profiling of Human Endogenous Retrovirus Group HERV-K(HML-2) Loci in Melanoma
por: Schmitt, Katja, et al.
Publicado: (2013)

The intron-enriched HERV-K(HML-10) family suppresses apoptosis, an indicator of malignant transformation
por: Broecker, Felix, et al.
Publicado: (2016)

High Expression of HERV-K (HML-2) Might Stimulate Interferon in COVID-19 Patients
por: Guo, Yaolin, et al.
Publicado: (2022)

Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project
por: Flockerzi, Aline, et al.
Publicado: (2008)

Identification of the protease cleavage sites in a reconstituted Gag polyprotein of an HERV-K(HML-2) element
por: George, Maja, et al.
Publicado: (2011)

Significant Upregulation of HERV-K (HML-2) Transcription Levels in Human Lung Cancer and Cancer Cells
por: Yang, Caiqin, et al.
Publicado: (2022)

Cross-Sectional Dating of Novel Haplotypes of HERV-K 113 and HERV-K 115 Indicate These Proviruses Originated in Africa before Homo sapiens
por: Jha, Aashish R., et al.
Publicado: (2009)

Preferential expression of human endogenous retrovirus K (HERV-K/HML-2) type 1 in tumor cells
por: Romano, Camila M, et al.
Publicado: (2011)

Differential expression of an endogenous retroviral element [HERV-K(HML-6)] is associated with reduced survival in glioblastoma patients
por: Shah, Ashish H., et al.
Publicado: (2022)

Contribution of type W human endogenous retroviruses to the human genome: characterization of HERV-W proviral insertions and processed pseudogenes
por: Grandi, Nicole, et al.
Publicado: (2016)

HERV-K(HML-2) rec and np9 transcripts not restricted to disease but present in many normal human tissues
por: Schmitt, Katja, et al.
Publicado: (2015)

Increased HERV-K(HML-2) Transcript Levels Correlate with Clinical Parameters of Liver Damage in Hepatitis C Patients
por: Weber, Melanie, et al.
Publicado: (2021)

Prolonged activity of HERV-K(HML2) in Old World Monkeys accounts for recent integrations and novel recombinant variants
por: Chabukswar, Saili, et al.
Publicado: (2022)

DNA methylation and expression of LINE-1 and HERV-K provirus sequences in urothelial and renal cell carcinomas
por: Florl, A R, et al.
Publicado: (1999)

Characterising a human endogenous retrovirus(HERV)-derived tumour-associated antigen: enriched RNA-Seq analysis of HERV-K(HML-2) in mantle cell lymphoma cell lines
por: Tatkiewicz, Witold, et al.
Publicado: (2020)

Identification and analysis of HML2 sequences in human genome assembly GRCh37/hg19
por: Cadeddu, Marta, et al.
Publicado: (2013)

Correction to: Characterising a human endogenous retrovirus(HERV)-derived tumour-associated antigen: enriched RNA-Seq analysis of HERV-K(HML-2) in mantle cell lymphoma cell lines
por: Tatkiewicz, Witold, et al.
Publicado: (2020)

Human endogenous retrovirus HERV-K(HML-2) encodes a stable signal peptide with biological properties distinct from Rec
por: Ruggieri, Alessia, et al.
Publicado: (2009)

Trans-activation, post-transcriptional maturation, and induction of antibodies to HERV-K (HML-2) envelope transmembrane protein in HIV-1 infection
por: Michaud, Henri-Alexandre, et al.
Publicado: (2014)

Minimal Absent Words in Four Human Genome Assemblies
por: Garcia, Sara P., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_81vigsov45l4vop5h5kf8pnkub