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Dysregulated transcriptional and post-translational control of DNA methyltransferases in cancer

Cancer is a leading cause of death worldwide. Aberrant promoter hypermethylation of CpG islands associated with tumor suppressor genes can lead to transcriptional silencing and result in tumorigenesis. DNA methyltransferases (DNMTs) are the enzymes responsible for DNA methylation and have been repor...

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Detalles Bibliográficos
Autores principales:	Lin, Ruo-Kai, Wang, Yi-Ching
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422219/ https://www.ncbi.nlm.nih.gov/pubmed/25949795 http://dx.doi.org/10.1186/2045-3701-4-46

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