Effect of levosimendan on the contractility of muscle fibers from nemaline myopathy patients with mutations in the nebulin gene

BACKGROUND: Nemaline myopathy (NM), the most common non-dystrophic congenital myopathy, is characterized by generalized skeletal muscle weakness, often from birth. To date, no therapy exists that enhances the contractile strength of muscles of NM patients. Mutations in NEB, encoding the giant protei...

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Detalles Bibliográficos
Autores principales: de Winter, Josine M, Joureau, Barbara, Sequeira, Vasco, Clarke, Nigel F, van der Velden, Jolanda, Stienen, Ger JM, Granzier, Henk, Beggs, Alan H, Ottenheijm, Coen AC
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422316/
https://www.ncbi.nlm.nih.gov/pubmed/25949787
http://dx.doi.org/10.1186/s13395-015-0037-7

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