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p38 mitogen-activated protein kinase is involved in arginase-II-mediated eNOS-Uncoupling in Obesity

BACKGROUND: Endothelial nitric oxide synthase (eNOS)-uncoupling links obesity-associated insulin resistance and type-II diabetes to the increased incidence of cardiovascular disease. Studies have indicated that increased arginase is involved in eNOS-uncoupling through competing with the substrate L-...

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Detalles Bibliográficos
Autores principales:	Yu, Yi, Rajapakse, Angana G, Montani, Jean-Pierre, Yang, Zhihong, Ming, Xiu-Fen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422321/ https://www.ncbi.nlm.nih.gov/pubmed/25034973 http://dx.doi.org/10.1186/s12933-014-0113-z

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