Tissue-specific patterns of gene expression in the epithelium and stroma of normal colon in healthy individuals in an aspirin intervention trial

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BACKGROUND: Regular aspirin use reduces colon adenoma and carcinoma incidence. UDP-glucuronosyltransferases (UGT) are involved in aspirin metabolism and clearance, and variant alleles in UGT1A6 have been shown to alter salicylic acid metabolism and risk of colon neoplasia. METHODS: In a randomized,...

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Detalles Bibliográficos
Autores principales: Thomas, Sushma S, Makar, Karen W, Li, Lin, Zheng, Yingye, Yang, Peiying, Levy, Lisa, Rudolph, Rebecca Yvonne, Lampe, Paul D, Yan, Min, Markowitz, Sanford D, Bigler, Jeannette, Lampe, Johanna W, Potter, John D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422425/
https://www.ncbi.nlm.nih.gov/pubmed/25927723
http://dx.doi.org/10.1186/s12881-015-0161-6
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