Long lasting control of viral rebound with a new drug ABX464 targeting Rev – mediated viral RNA biogenesis

BACKGROUND: Current therapies have succeeded in controlling AIDS pandemic. However, there is a continuing need for new drugs, in particular those acting through new and as yet unexplored mechanisms of action to achieve HIV infection cure. We took advantage of the unique feature of proviral genome to...

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Detalles Bibliográficos
Autores principales: Campos, Noëlie, Myburgh, Renier, Garcel, Aude, Vautrin, Audrey, Lapasset, Laure, Nadal, Erika Schläpfer, Mahuteau-Betzer, Florence, Najman, Romain, Fornarelli, Pauline, Tantale, Katjana, Basyuk, Eugénia, Séveno, Martial, Venables, Julian P, Pau, Bernard, Bertrand, Edouard, Wainberg, Mark A, Speck, Roberto F, Scherrer, Didier, Tazi, Jamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422473/
https://www.ncbi.nlm.nih.gov/pubmed/25889234
http://dx.doi.org/10.1186/s12977-015-0159-3

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