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Sexual Dimorphism in MAPK-Activated Protein Kinase-2 (MK2) Regulation of RANKL-Induced Osteoclastogenesis in Osteoclast Progenitor Subpopulations

Osteoclasts (OCs) are bone-resorptive cells critical for maintaining skeletal integrity through coupled bone turnover. OC differentiation and activation requires receptor activator of NF-kB ligand (RANKL) signaling through the p38 MAPK pathway. However the role of the p38 MAPK substrate, MAPK-activa...

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Detalles Bibliográficos
Autores principales:	Herbert, Bethany A., Valerio, Michael S., Gaestel, Matthias, Kirkwood, Keith L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422514/ https://www.ncbi.nlm.nih.gov/pubmed/25946081 http://dx.doi.org/10.1371/journal.pone.0125387

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