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The transcription factor MITF is a critical regulator of GPNMB expression in dendritic cells
BACKGROUND: Dendritic cells (DC) are the most potent antigen-presenting cells (APC) with the unique ability to activate naïve T cells and to initiate and maintain primary immune responses. Immunosuppressive and anti-inflammatory stimuli on DC such as the cytokine IL-10 suppress the activity of the t...
Autores principales: | Gutknecht, Michael, Geiger, Julian, Joas, Simone, Dörfel, Daniela, Salih, Helmut R, Müller, Martin R, Grünebach, Frank, Rittig, Susanne M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422548/ https://www.ncbi.nlm.nih.gov/pubmed/25889792 http://dx.doi.org/10.1186/s12964-015-0099-5 |
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