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Processing of Neutrophil α-Defensins Does Not Rely on Serine Proteases In Vivo
The α-defensins, human neutrophil peptides (HNPs) are the predominant antimicrobial peptides of neutrophil granules. They are synthesized in promyelocytes and myelocytes as proHNPs, but only processed in promyelocytes and stored as mature HNPs in azurophil granules. Despite decades of search, the me...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422583/ https://www.ncbi.nlm.nih.gov/pubmed/25945506 http://dx.doi.org/10.1371/journal.pone.0125483 |