A General Model of Negative Frequency Dependent Selection Explains Global Patterns of Human ABO Polymorphism

The ABO locus in humans is characterized by elevated heterozygosity and very similar allele frequencies among populations scattered across the globe. Using knowledge of ABO protein function, we generated a simple model of asymmetric negative frequency dependent selection and genetic drift to explain...

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Detalles Bibliográficos
Autores principales: Villanea, Fernando A., Safi, Kristin N., Busch, Jeremiah W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422588/
https://www.ncbi.nlm.nih.gov/pubmed/25946124
http://dx.doi.org/10.1371/journal.pone.0125003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422588/
https://www.ncbi.nlm.nih.gov/pubmed/25946124
http://dx.doi.org/10.1371/journal.pone.0125003

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