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Mutations in RECQL Gene Are Associated with Predisposition to Breast Cancer
The genetic cause for approximately 80% of familial breast cancer patients is unknown. Here, by sequencing the entire exomes of nine early-onset familial breast cancer patients without BRCA1/2 mutations (diagnosed with breast cancer at or before the age of 35) we found that two index cases carried a...
Autores principales: | Sun, Jie, Wang, Yuxia, Xia, Yisui, Xu, Ye, Ouyang, Tao, Li, Jinfeng, Wang, Tianfeng, Fan, Zhaoqing, Fan, Tie, Lin, Benyao, Lou, Huiqiang, Xie, Yuntao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422667/ https://www.ncbi.nlm.nih.gov/pubmed/25945795 http://dx.doi.org/10.1371/journal.pgen.1005228 |
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