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Development of a Cell-Based Bioassay for Phospholipase A(2)-Triggered Liposomal Drug Release
The feasibility of exploiting secretory phospholipase A(2) (sPLA(2)) enzymes, which are overexpressed in tumors, to activate drug release from liposomes precisely at the tumor site has been demonstrated before. Although the efficacy of the developed formulations was evaluated using in vitro and in v...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422686/ https://www.ncbi.nlm.nih.gov/pubmed/25945937 http://dx.doi.org/10.1371/journal.pone.0125508 |