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Pandemic Swine-Origin H1N1 Influenza Virus Replicates to Higher Levels and Induces More Fever and Acute Inflammatory Cytokines in Cynomolgus versus Rhesus Monkeys and Can Replicate in Common Marmosets
The close immunological and physiological resemblance with humans makes non-human primates a valuable model for studying influenza virus pathogenesis and immunity and vaccine efficacy against infection. Although both cynomolgus and rhesus macaques are frequently used in influenza virus research, a d...
Autores principales: | Mooij, Petra, Koopman, Gerrit, Mortier, Daniëlla, van Heteren, Melanie, Oostermeijer, Herman, Fagrouch, Zahra, de Laat, Rudy, Kobinger, Gary, Li, Yan, Remarque, Edmond J., Kondova, Ivanela, Verschoor, Ernst J., Bogers, Willy M. J. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422689/ https://www.ncbi.nlm.nih.gov/pubmed/25946071 http://dx.doi.org/10.1371/journal.pone.0126132 |
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