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The Role of Structural Dynamics of Actin in Class-Specific Myosin Motility

The structural dynamics of actin, including the tilting motion between the small and large domains, are essential for proper interactions with actin-binding proteins. Gly146 is situated at the hinge between the two domains, and we previously showed that a G146V mutation leads to severe motility defe...

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Detalles Bibliográficos
Autores principales: Noguchi, Taro Q. P., Morimatsu, Masatoshi, Iwane, Atsuko H., Yanagida, Toshio, Uyeda, Taro Q. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422724/
https://www.ncbi.nlm.nih.gov/pubmed/25945499
http://dx.doi.org/10.1371/journal.pone.0126262