Agonist signalling properties of radiotracers used for imaging of dopamine D(2/3) receptors

BACKGROUND: Dopamine D(2/3) receptor (D(2/3)R) agonist radiopharmaceuticals are considered superior to antagonists to detect dopamine release, e.g. induced by amphetamines. Agonists bind preferentially to the high-affinity state of the dopamine D(2)R, which has been proposed as the reason why agonis...

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Detalles Bibliográficos
Autores principales: van Wieringen, Jan-Peter, Michel, Martin C, Janssen, Henk M, Janssen, Anton G, Elsinga, Philip H, Booij, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422956/
https://www.ncbi.nlm.nih.gov/pubmed/25977878
http://dx.doi.org/10.1186/s13550-014-0053-3

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