Epigenetic silencing of microRNA-149 in cancer-associated fibroblasts mediates prostaglandin E2/interleukin-6 signaling in the tumor microenvironment

Tumor initiation and growth depend on its microenvironment in which cancer-associated fibroblasts (CAFs) in tumor stroma play an important role. Prostaglandin E2 (PGE2) and interleukin (IL)-6 signal pathways are involved in the crosstalk between tumor and stromal cells. However, how PGE2-mediated si...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Pu, Shan, Jing-Xuan, Chen, Xue-Hua, Zhang, Di, Su, Li-Ping, Huang, Xiu-Ying, Yu, Bei-Qin, Zhi, Qiao-Ming, Li, Cheng-Long, Wang, Ya-Qing, Tomei, Sara, Cai, Qu, Ji, Jun, Li, Jian-Fang, Chouchane, Lotfi, Yu, Ying-Yan, Sun, Fang-Zhen, Xu, Zhi-Heng, Liu, Bing-Ya, Zhu, Zheng-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423088/
https://www.ncbi.nlm.nih.gov/pubmed/25916550
http://dx.doi.org/10.1038/cr.2015.51

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423088/
https://www.ncbi.nlm.nih.gov/pubmed/25916550
http://dx.doi.org/10.1038/cr.2015.51

Ejemplares similares