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Epigenetic silencing of microRNA-149 in cancer-associated fibroblasts mediates prostaglandin E2/interleukin-6 signaling in the tumor microenvironment

Tumor initiation and growth depend on its microenvironment in which cancer-associated fibroblasts (CAFs) in tumor stroma play an important role. Prostaglandin E2 (PGE2) and interleukin (IL)-6 signal pathways are involved in the crosstalk between tumor and stromal cells. However, how PGE2-mediated si...

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Detalles Bibliográficos
Autores principales:	Li, Pu, Shan, Jing-Xuan, Chen, Xue-Hua, Zhang, Di, Su, Li-Ping, Huang, Xiu-Ying, Yu, Bei-Qin, Zhi, Qiao-Ming, Li, Cheng-Long, Wang, Ya-Qing, Tomei, Sara, Cai, Qu, Ji, Jun, Li, Jian-Fang, Chouchane, Lotfi, Yu, Ying-Yan, Sun, Fang-Zhen, Xu, Zhi-Heng, Liu, Bing-Ya, Zhu, Zheng-Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423088/ https://www.ncbi.nlm.nih.gov/pubmed/25916550 http://dx.doi.org/10.1038/cr.2015.51

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